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rxlist.com Austedo Keywords Valbenazine Trade Name: Ingrezza Drug Class: Rx of Tardive dyskinesia (monoamine depletor) Mechanism of Action: a selective competitive inhibitor of VMAT2, similar to tetrabenazine the monoamine vesicular monoamine uptake transporter (VMAT2) transports (loads) cytoplasmic monoamine neurotransmitters (dopamine, norepinephrine, histamine, serotonin) into presynaptic storage vesicles found in sympathetic nerve terminals

The kill switch of engineered live bacteria is difficult to maintain stability due to the application of strong selective pressure, and there may be a risk of escape mutations in the bacterial community in complex environments

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